Early modern. Historian Charles Keenan showed in 2023 that nuncios "performed much of the same intelligence work" as other diplomats, especially on England and Poland-Lithuania. The papacy kept cipher secretaries from the Renaissance onward.
The Inquisition gathered denunciations and testimony, but it was a court, not an intelligence service. Individual Jesuits were caught in plots (Henry Garnet was executed after the Gunpowder Plot); there was never an order-wide spy network.
1870 onward. David Alvarez's Spies in the Vatican argues the formal papal intelligence effort effectively ended with the loss of the Papal States. In WWII, Germany, Italy, the USSR and the US all spied on it. A Nazi scheme to plant officers as seminarians failed partly because the men were "more interested in women than the cloistered life".
Cold War. KGB documents call the Vatican "one of the main targets of observation and penetration". Polish SB files exposed the Dominican Konrad Hejmo as an informant close to John Paul II. The Soviet-bloc link to the 1981 shooting is Disputed: backed by the Mitrokhin Commission, never proved in court.
Today. The Gendarmerie and the Swiss Guard handle security; the ASIF handles financial intelligence. In 2012 the Vatican admitted authorising "some intercepts" during Vatileaks.
VerdictThe popes ran diplomats who gathered information like every court did. But the Vatican was spied on far more than it spied, and its reputation for the "best intelligence service in the world" is, in Alvarez's words, more myth than reality.